GMP reductase 2
2c6q B 68 B 95
A redox-regulated disulphide may form within GMP reductase 2 between cysteines 68 and 95.
Details
Redox score ?
78
PDB code
2c6q
Structure name
crystal structure of human guanosine monophosphate reductase 2 gmpr2 in complex with imp and nadph
Structure deposition date
2005-11-11
Thiol separation (Å)
3
Half-sphere exposure sum ?
60
Minimum pKa ?
10
% buried
40
Peptide accession
Q9P2T1
Residue number A
68
Residue number B
95
Peptide name
GMP reductase 2
Ligandability
Cysteine 68 of GMP reductase 2
Cysteine 95 of GMP reductase 2
2a7r C 222 C 224
A redox-regulated disulphide may form within GMP reductase 2 between cysteines 222 and 224. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
2a7r
Structure name
crystal structure of human guanosine monophosphate reductase 2 (gmpr2)
Structure deposition date
2005-07-05
Thiol separation (Å)
7
Half-sphere exposure sum ?
70
Minimum pKa ?
11
% buried
82
Peptide accession
Q9P2T1
Residue number A
222
Residue number B
224
Peptide name
GMP reductase 2
Ligandability
Cysteine 222 of GMP reductase 2
Cysteine 224 of GMP reductase 2
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