ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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PTB domain-containing engulfment adapter protein 1

Intramolecular
Cysteine 93 and cysteine 115
A redox-regulated disulphide may form within PTB domain-containing engulfment adapter protein 1 between cysteines 93 and 115.

Details

Redox score ?
71
PDB code
6itu
Structure name
crystal structure of the gulp1 ptb domain-app peptide complex
Structure deposition date
2018-11-26
Thiol separation (Å)
4
Half-sphere exposure sum ?
73
Minimum pKa ?
7
% buried
87
Peptide accession
Q9UBP9
Residue number A
93
Residue number B
115
Peptide name
PTB domain-containing engulfment adapter protein 1

Ligandability

Cysteine 93 of PTB domain-containing engulfment adapter protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 115 of PTB domain-containing engulfment adapter protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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