ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Eukaryotic translation initiation factor 3 subunit K

Intramolecular
Cysteine 85 and cysteine 87
A redox-regulated disulphide may form within Eukaryotic translation initiation factor 3 subunit K between cysteines 85 and 87. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
1rz4
Structure name
crystal structure of human eif3k
Structure deposition date
2003-12-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
10
% buried
64
Peptide accession
Q9UBQ5
Residue number A
85
Residue number B
87
Peptide name
Eukaryotic translation initiation factor 3 subunit K

Ligandability

Cysteine 85 of Eukaryotic translation initiation factor 3 subunit K

Cysteine 87 of Eukaryotic translation initiation factor 3 subunit K

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