a tool for identifying drug-targetable redox-active disulphides

Exostosin-like 2

Intramolecular

Cysteine 244 and cysteine 296

A redox-regulated disulphide may form within Exostosin-like 2 between cysteines 244 and 296.

Details

Redox score ?

82

PDB code

Structure name

crystal structure of mouse alpha-1,4-n-acetylhexosaminyltransferase (extl2)

Structure deposition date

2003-02-26

Thiol separation (Å)

2

Half-sphere exposure sum ?

77

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

244

Residue number B

296

Peptide name

Exostosin-like 2

Ligandability

Cysteine 244 of Exostosin-like 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 296 of Exostosin-like 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: