a tool for identifying drug-targetable redox-active disulphides

Beta-1,4-galactosyltransferase 7

Intramolecular

Cysteine 316 and cysteine 324

A redox-regulated disulphide may form within Beta-1,4-galactosyltransferase 7 between cysteines 316 and 324.

Details

Redox score ?

86

PDB code

Structure name

crystal structure of catalytic domain of human beta1, 4galactosyltransferase 7 in closed conformation in complex with manganese and udp

Structure deposition date

2013-01-15

Thiol separation (Å)

2

Half-sphere exposure sum ?

60

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

316

Residue number B

324

Peptide name

Beta-1,4-galactosyltransferase 7

Ligandability

Cysteine 316 of Beta-1,4-galactosyltransferase 7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 324 of Beta-1,4-galactosyltransferase 7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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