ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Serine/threonine-protein kinase 17A

Intramolecular
Cysteine 62 and cysteine 78
A redox-regulated disulphide may form within Serine/threonine-protein kinase 17A between cysteines 62 and 78.

Details

Redox score ?
63
PDB code
7que
Structure name
the stk17a (drak1) kinase domain bound to ckjb68
Structure deposition date
2022-01-17
Thiol separation (Å)
6
Half-sphere exposure sum ?
55
Minimum pKa ?
10
% buried
14
Peptide accession
Q9UEE5
Residue number A
62
Residue number B
78
Peptide name
Serine/threonine-protein kinase 17A

Ligandability

Cysteine 62 of Serine/threonine-protein kinase 17A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 78 of Serine/threonine-protein kinase 17A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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