a tool for identifying drug-targetable redox-active disulphides

Death domain-associated protein 6

Intramolecular

Cysteine 240 and cysteine 245 L

A redox-regulated disulphide may form within Death domain-associated protein 6 between cysteines 240 and 245.

Details

Redox score ?

76

PDB code

Structure name

complex structure 6 of daxx/h3

Structure deposition date

2012-09-24

Thiol separation (Å)

4

Half-sphere exposure sum ?

38

Minimum pK_a ?

9

% buried

24

Peptide accession

Residue number A

240

Residue number B

245

Peptide name

Death domain-associated protein 6

Ligandability

Cysteine 240 of Death domain-associated protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 245 of Death domain-associated protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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