ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

GTPase IMAP family member 2

Intramolecular
Cysteine 61 and cysteine 98
Cysteine 180 and cysteine 201
A redox-regulated disulphide may form within GTPase IMAP family member 2 between cysteines 61 and 98.

Details

Redox score ?
70
PDB code
3p1j
Structure name
crystal structure of human gtpase imap family member 2 in the nucleotide-free state
Structure deposition date
2010-09-30
Thiol separation (Å)
5
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9UG22
Residue number A
61
Residue number B
98
Peptide name
GTPase IMAP family member 2

Ligandability

Cysteine 61 of GTPase IMAP family member 2

Cysteine 98 of GTPase IMAP family member 2

A redox-regulated disulphide may form within GTPase IMAP family member 2 between cysteines 180 and 201.

Details

Redox score ?
68
PDB code
3p1j
Structure name
crystal structure of human gtpase imap family member 2 in the nucleotide-free state
Structure deposition date
2010-09-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9UG22
Residue number A
180
Residue number B
201
Peptide name
GTPase IMAP family member 2

Ligandability

Cysteine 180 of GTPase IMAP family member 2

Cysteine 201 of GTPase IMAP family member 2

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