ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Sushi domain-containing protein 2

Intramolecular
Cysteine 33 and cysteine 60
Cysteine 46 and cysteine 52
Cysteine 29 and cysteine 42
Cysteine 40 and cysteine 53
Cysteine 29 and cysteine 53
Cysteine 29 and cysteine 40
Cysteine 29 and cysteine 60
Cysteine 42 and cysteine 53
Cysteine 40 and cysteine 42
Cysteine 29 and cysteine 33
More...
Cysteine 42 and cysteine 60
Cysteine 46 and cysteine 53
Cysteine 33 and cysteine 42
Cysteine 29 and cysteine 46
Cysteine 53 and cysteine 60
Cysteine 52 and cysteine 53
Cysteine 40 and cysteine 46
Cysteine 46 and cysteine 60
Cysteine 42 and cysteine 46
Cysteine 29 and cysteine 52
Cysteine 33 and cysteine 53
Cysteine 40 and cysteine 52
Cysteine 40 and cysteine 60
Cysteine 33 and cysteine 46
Cysteine 52 and cysteine 60
Cysteine 42 and cysteine 52
Cysteine 33 and cysteine 40
A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 33 and 60 (25 and 52 respectively in this structure).

Details

Redox score ?
87
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
33
Residue number B
60
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 33 of Sushi domain-containing protein 2

Cysteine 60 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 46 and 52 (38 and 44 respectively in this structure).

Details

Redox score ?
87
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
46
Residue number B
52
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 46 of Sushi domain-containing protein 2

Cysteine 52 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 29 and 42 (21 and 34 respectively in this structure).

Details

Redox score ?
86
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
29
Residue number B
42
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 29 of Sushi domain-containing protein 2

Cysteine 42 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 40 and 53 (32 and 45 respectively in this structure).

Details

Redox score ?
83
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
40
Residue number B
53
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 40 of Sushi domain-containing protein 2

Cysteine 53 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 29 and 53 (21 and 45 respectively in this structure).

Details

Redox score ?
82
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
3
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
29
Residue number B
53
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 29 of Sushi domain-containing protein 2

Cysteine 53 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 29 and 40 (21 and 32 respectively in this structure).

Details

Redox score ?
74
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
29
Residue number B
40
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 29 of Sushi domain-containing protein 2

Cysteine 40 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 29 and 60 (21 and 52 respectively in this structure).

Details

Redox score ?
73
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
5
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
29
Residue number B
60
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 29 of Sushi domain-containing protein 2

Cysteine 60 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 42 and 53 (34 and 45 respectively in this structure).

Details

Redox score ?
71
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
42
Residue number B
53
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 42 of Sushi domain-containing protein 2

Cysteine 53 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 40 and 42 (32 and 34 respectively in this structure).

Details

Redox score ?
68
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
5
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
40
Residue number B
42
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 40 of Sushi domain-containing protein 2

Cysteine 42 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 29 and 33 (21 and 25 respectively in this structure).

Details

Redox score ?
65
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
6
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
29
Residue number B
33
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 29 of Sushi domain-containing protein 2

Cysteine 33 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 42 and 60 (34 and 52 respectively in this structure).

Details

Redox score ?
64
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
6
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
42
Residue number B
60
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 42 of Sushi domain-containing protein 2

Cysteine 60 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 46 and 53 (38 and 45 respectively in this structure).

Details

Redox score ?
60
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
7
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
46
Residue number B
53
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 46 of Sushi domain-containing protein 2

Cysteine 53 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 33 and 42 (25 and 34 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
58
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
6
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
33
Residue number B
42
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 33 of Sushi domain-containing protein 2

Cysteine 42 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 29 and 46 (21 and 38 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
58
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
29
Residue number B
46
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 29 of Sushi domain-containing protein 2

Cysteine 46 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 53 and 60 (45 and 52 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
57
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
7
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
53
Residue number B
60
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 53 of Sushi domain-containing protein 2

Cysteine 60 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 52 and 53 (44 and 45 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
54
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
7
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
52
Residue number B
53
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 52 of Sushi domain-containing protein 2

Cysteine 53 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 40 and 46 (32 and 38 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
53
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
40
Residue number B
46
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 40 of Sushi domain-containing protein 2

Cysteine 46 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 46 and 60 (38 and 52 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
46
Residue number B
60
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 46 of Sushi domain-containing protein 2

Cysteine 60 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 42 and 46 (34 and 38 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
42
Residue number B
46
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 42 of Sushi domain-containing protein 2

Cysteine 46 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 29 and 52 (21 and 44 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
49
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
29
Residue number B
52
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 29 of Sushi domain-containing protein 2

Cysteine 52 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 33 and 53 (25 and 45 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
33
Residue number B
53
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 33 of Sushi domain-containing protein 2

Cysteine 53 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 40 and 52 (32 and 44 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
40
Residue number B
52
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 40 of Sushi domain-containing protein 2

Cysteine 52 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 40 and 60 (32 and 52 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
9
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
40
Residue number B
60
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 40 of Sushi domain-containing protein 2

Cysteine 60 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 33 and 46 (25 and 38 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
33
Residue number B
46
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 33 of Sushi domain-containing protein 2

Cysteine 46 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 52 and 60 (44 and 52 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
52
Residue number B
60
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 52 of Sushi domain-containing protein 2

Cysteine 60 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 42 and 52 (34 and 44 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
39
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
42
Residue number B
52
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 42 of Sushi domain-containing protein 2

Cysteine 52 of Sushi domain-containing protein 2

A redox-regulated disulphide may form within Sushi domain-containing protein 2 between cysteines 33 and 40 (25 and 32 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
38
PDB code
2cqw
Structure name
solution structure of rsgi ruh-041, a smb-like domain from mouse cdna
Structure deposition date
2005-05-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9DBX3
Residue number A
33
Residue number B
40
Peptide name
Sushi domain-containing protein 2

Ligandability

Cysteine 33 of Sushi domain-containing protein 2

Cysteine 40 of Sushi domain-containing protein 2

If this tool was useful for finding a disulphide, please cite: