ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Interleukin-20 receptor subunit alpha

Intramolecular
Cysteine 87 and cysteine 95
Cysteine 215 and cysteine 236
A redox-regulated disulphide may form within Interleukin-20 receptor subunit alpha between cysteines 87 and 95.

Details

Redox score ?
86
PDB code
4doh
Structure name
il20/il201/il20r2 ternary complex
Structure deposition date
2012-02-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9UHF4
Residue number A
87
Residue number B
95
Peptide name
Interleukin-20 receptor subunit alpha

Ligandability

Cysteine 87 of Interleukin-20 receptor subunit alpha

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 95 of Interleukin-20 receptor subunit alpha

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Interleukin-20 receptor subunit alpha between cysteines 215 and 236.

Details

Redox score ?
80
PDB code
4doh
Structure name
il20/il201/il20r2 ternary complex
Structure deposition date
2012-02-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9UHF4
Residue number A
215
Residue number B
236
Peptide name
Interleukin-20 receptor subunit alpha

Ligandability

Cysteine 215 of Interleukin-20 receptor subunit alpha

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 236 of Interleukin-20 receptor subunit alpha

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: