Probable ATP-dependent RNA helicase DDX20

Intermolecular

Intramolecular

A redox-regulated disulphide may form between two units of Probable ATP-dependent RNA helicase DDX20 at cysteines 98 and 98. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

3b7g

Structure name

human dead-box rna helicase ddx20, conserved domain i (dead) in complex with amppnp (adenosine-(beta,gamma)-imidotriphosphate)

Structure deposition date

2007-10-30

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Probable ATP-dependent RNA helicase DDX20

Peptide B name

Probable ATP-dependent RNA helicase DDX20

Peptide A accession

Q9UHI6

Peptide B accession

Q9UHI6

Peptide A residue number

Peptide B residue number

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Probable ATP-dependent RNA helicase DDX20 between cysteines 162 and 181. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?