Prefoldin subunit 2

Intermolecular

Cysteine 70 and cysteine 124 of Prefoldin subunit 3

A redox-regulated disulphide may form between cysteine 70 of Prefoldin subunit 2 and cysteine 124 of Prefoldin subunit 3. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7wu7

Structure name

prefoldin-tubulin-tric complex

Structure deposition date

2022-02-07

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Prefoldin subunit 2

Peptide B name

Prefoldin subunit 3

Peptide A accession

Q9UHV9

Peptide B accession

P61758

Peptide A residue number

Peptide B residue number

124

Ligandability

Cysteine 70 of Prefoldin subunit 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.