a tool for identifying drug-targetable redox-active disulphides

Krueppel-like factor 15

Intramolecular

Cysteine 353 and cysteine 358

A redox-regulated disulphide may form within Krueppel-like factor 15 between cysteines 353 and 358.

Details

Redox score ?

81

PDB code

Structure name

solution structure of the second c2h2-type zinc finger domain from human krueppel-like factor 15

Structure deposition date

2007-03-28

Thiol separation (Å)

4

Half-sphere exposure sum ?

40

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

353

Residue number B

358

Peptide name

Krueppel-like factor 15

Ligandability

Cysteine 353 of Krueppel-like factor 15

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 358 of Krueppel-like factor 15

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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