ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Plexin-A1

Intramolecular
Cysteine 93 and cysteine 102 L
Cysteine 665 and cysteine 704
Cysteine 1195 and cysteine 1206
Cysteine 1092 and cysteine 1102
Cysteine 999 and cysteine 1011
Cysteine 829 and cysteine 841
Cysteine 513 and cysteine 530
Cysteine 374 and cysteine 393
Cysteine 905 and cysteine 920
Cysteine 678 and cysteine 691
More...
Cysteine 668 and cysteine 684
Cysteine 522 and cysteine 539
Cysteine 519 and cysteine 561
Cysteine 659 and cysteine 675
Cysteine 284 and cysteine 405
Cysteine 814 and cysteine 859
Cysteine 533 and cysteine 545
Cysteine 807 and cysteine 826
Cysteine 596 and cysteine 615
Cysteine 938 and cysteine 942
Cysteine 817 and cysteine 835
Cysteine 742 and cysteine 765
Cysteine 300 and cysteine 356
Cysteine 128 and cysteine 136
Cysteine 513 and cysteine 539
Cysteine 826 and cysteine 835
Cysteine 675 and cysteine 684
Cysteine 530 and cysteine 539
Cysteine 668 and cysteine 675
Cysteine 659 and cysteine 684
Cysteine 817 and cysteine 826
Cysteine 807 and cysteine 835
Cysteine 659 and cysteine 668
Cysteine 513 and cysteine 522
Cysteine 522 and cysteine 530
Cysteine 519 and cysteine 522
Cysteine 665 and cysteine 668
Cysteine 807 and cysteine 817
Cysteine 668 and cysteine 691
Cysteine 668 and cysteine 704
A redox-regulated disulphide may form within Plexin-A1 between cysteines 93 and 102.

Details

Redox score ?
89
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
93
Residue number B
102
Peptide name
Plexin-A1

Ligandability

Cysteine 93 of Plexin-A1

Cysteine 102 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 665 and 704.

Details

Redox score ?
88
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
665
Residue number B
704
Peptide name
Plexin-A1

Ligandability

Cysteine 665 of Plexin-A1

Cysteine 704 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 1195 and 1206.

Details

Redox score ?
87
PDB code
5l7n
Structure name
plexin a1 extracellular fragment, domains 7-10 (ipt3-ipt6)
Structure deposition date
2016-06-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
1195
Residue number B
1206
Peptide name
Plexin-A1

Ligandability

Cysteine 1195 of Plexin-A1

Cysteine 1206 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 1092 and 1102.

Details

Redox score ?
87
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
1092
Residue number B
1102
Peptide name
Plexin-A1

Ligandability

Cysteine 1092 of Plexin-A1

Cysteine 1102 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 999 and 1011.

Details

Redox score ?
86
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
999
Residue number B
1011
Peptide name
Plexin-A1

Ligandability

Cysteine 999 of Plexin-A1

Cysteine 1011 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 829 and 841.

Details

Redox score ?
86
PDB code
5l56
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 4 angstrom
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
829
Residue number B
841
Peptide name
Plexin-A1

Ligandability

Cysteine 829 of Plexin-A1

Cysteine 841 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 513 and 530.

Details

Redox score ?
86
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
513
Residue number B
530
Peptide name
Plexin-A1

Ligandability

Cysteine 513 of Plexin-A1

Cysteine 530 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 374 and 393.

Details

Redox score ?
86
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
374
Residue number B
393
Peptide name
Plexin-A1

Ligandability

Cysteine 374 of Plexin-A1

Cysteine 393 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 905 and 920.

Details

Redox score ?
85
PDB code
5l56
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 4 angstrom
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
905
Residue number B
920
Peptide name
Plexin-A1

Ligandability

Cysteine 905 of Plexin-A1

Cysteine 920 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 678 and 691.

Details

Redox score ?
84
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
678
Residue number B
691
Peptide name
Plexin-A1

Ligandability

Cysteine 678 of Plexin-A1

Cysteine 691 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 668 and 684.

Details

Redox score ?
84
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
668
Residue number B
684
Peptide name
Plexin-A1

Ligandability

Cysteine 668 of Plexin-A1

Cysteine 684 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 522 and 539.

Details

Redox score ?
83
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
522
Residue number B
539
Peptide name
Plexin-A1

Ligandability

Cysteine 522 of Plexin-A1

Cysteine 539 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 519 and 561.

Details

Redox score ?
83
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
519
Residue number B
561
Peptide name
Plexin-A1

Ligandability

Cysteine 519 of Plexin-A1

Cysteine 561 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 659 and 675.

Details

Redox score ?
83
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
659
Residue number B
675
Peptide name
Plexin-A1

Ligandability

Cysteine 659 of Plexin-A1

Cysteine 675 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 284 and 405.

Details

Redox score ?
83
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
284
Residue number B
405
Peptide name
Plexin-A1

Ligandability

Cysteine 284 of Plexin-A1

Cysteine 405 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 814 and 859.

Details

Redox score ?
82
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
814
Residue number B
859
Peptide name
Plexin-A1

Ligandability

Cysteine 814 of Plexin-A1

Cysteine 859 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 533 and 545.

Details

Redox score ?
82
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
533
Residue number B
545
Peptide name
Plexin-A1

Ligandability

Cysteine 533 of Plexin-A1

Cysteine 545 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 807 and 826.

Details

Redox score ?
81
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
807
Residue number B
826
Peptide name
Plexin-A1

Ligandability

Cysteine 807 of Plexin-A1

Cysteine 826 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 596 and 615.

Details

Redox score ?
81
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
596
Residue number B
615
Peptide name
Plexin-A1

Ligandability

Cysteine 596 of Plexin-A1

Cysteine 615 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 938 and 942.

Details

Redox score ?
81
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
938
Residue number B
942
Peptide name
Plexin-A1

Ligandability

Cysteine 938 of Plexin-A1

Cysteine 942 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 817 and 835.

Details

Redox score ?
81
PDB code
5l56
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 4 angstrom
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
817
Residue number B
835
Peptide name
Plexin-A1

Ligandability

Cysteine 817 of Plexin-A1

Cysteine 835 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 742 and 765.

Details

Redox score ?
81
PDB code
5l56
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 4 angstrom
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
742
Residue number B
765
Peptide name
Plexin-A1

Ligandability

Cysteine 742 of Plexin-A1

Cysteine 765 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 300 and 356.

Details

Redox score ?
79
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
300
Residue number B
356
Peptide name
Plexin-A1

Ligandability

Cysteine 300 of Plexin-A1

Cysteine 356 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 128 and 136.

Details

Redox score ?
77
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
90
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
128
Residue number B
136
Peptide name
Plexin-A1

Ligandability

Cysteine 128 of Plexin-A1

Cysteine 136 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 513 and 539.

Details

Redox score ?
71
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
513
Residue number B
539
Peptide name
Plexin-A1

Ligandability

Cysteine 513 of Plexin-A1

Cysteine 539 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 826 and 835.

Details

Redox score ?
71
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
826
Residue number B
835
Peptide name
Plexin-A1

Ligandability

Cysteine 826 of Plexin-A1

Cysteine 835 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 675 and 684.

Details

Redox score ?
70
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
675
Residue number B
684
Peptide name
Plexin-A1

Ligandability

Cysteine 675 of Plexin-A1

Cysteine 684 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 530 and 539.

Details

Redox score ?
68
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
530
Residue number B
539
Peptide name
Plexin-A1

Ligandability

Cysteine 530 of Plexin-A1

Cysteine 539 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 668 and 675.

Details

Redox score ?
68
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
668
Residue number B
675
Peptide name
Plexin-A1

Ligandability

Cysteine 668 of Plexin-A1

Cysteine 675 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 659 and 684.

Details

Redox score ?
67
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
659
Residue number B
684
Peptide name
Plexin-A1

Ligandability

Cysteine 659 of Plexin-A1

Cysteine 684 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 817 and 826.

Details

Redox score ?
65
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
817
Residue number B
826
Peptide name
Plexin-A1

Ligandability

Cysteine 817 of Plexin-A1

Cysteine 826 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 807 and 835.

Details

Redox score ?
63
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
807
Residue number B
835
Peptide name
Plexin-A1

Ligandability

Cysteine 807 of Plexin-A1

Cysteine 835 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 659 and 668.

Details

Redox score ?
63
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
659
Residue number B
668
Peptide name
Plexin-A1

Ligandability

Cysteine 659 of Plexin-A1

Cysteine 668 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 513 and 522.

Details

Redox score ?
63
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
513
Residue number B
522
Peptide name
Plexin-A1

Ligandability

Cysteine 513 of Plexin-A1

Cysteine 522 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 522 and 530.

Details

Redox score ?
62
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
522
Residue number B
530
Peptide name
Plexin-A1

Ligandability

Cysteine 522 of Plexin-A1

Cysteine 530 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 519 and 522. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
58
PDB code
5l5c
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p4(3)2(1)2
Structure deposition date
2016-05-28
Thiol separation (Å)
7
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
519
Residue number B
522
Peptide name
Plexin-A1

Ligandability

Cysteine 519 of Plexin-A1

Cysteine 522 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 665 and 668. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
56
PDB code
5l56
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 4 angstrom
Structure deposition date
2016-05-28
Thiol separation (Å)
7
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
665
Residue number B
668
Peptide name
Plexin-A1

Ligandability

Cysteine 665 of Plexin-A1

Cysteine 668 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 807 and 817. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
56
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
807
Residue number B
817
Peptide name
Plexin-A1

Ligandability

Cysteine 807 of Plexin-A1

Cysteine 817 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 668 and 691. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
5l56
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 4 angstrom
Structure deposition date
2016-05-28
Thiol separation (Å)
8
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
668
Residue number B
691
Peptide name
Plexin-A1

Ligandability

Cysteine 668 of Plexin-A1

Cysteine 691 of Plexin-A1

A redox-regulated disulphide may form within Plexin-A1 between cysteines 668 and 704. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
5l59
Structure name
plexin a1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup p2(1)
Structure deposition date
2016-05-28
Thiol separation (Å)
8
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70206
Residue number A
668
Residue number B
704
Peptide name
Plexin-A1

Ligandability

Cysteine 668 of Plexin-A1

Cysteine 704 of Plexin-A1

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