Dynactin subunit 4

Intermolecular

Cysteine 79 and cysteine 149 of Dynactin subunit 5

A redox-regulated disulphide may form between cysteine 79 of Dynactin subunit 4 and cysteine 149 of Dynactin subunit 5. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7z8m

Structure name

the pointed end complex of dynactin bound to bicdr1

Structure deposition date

2022-03-17

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Dynactin subunit 4

Peptide B name

Dynactin subunit 5

Peptide A accession

A0A4X1TB62

Peptide B accession

A0A286ZK88

Peptide A residue number

Peptide B residue number

149

Ligandability

Cysteine 79 of Dynactin subunit 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.