TRAF2 and NCK-interacting protein kinase

Intramolecular

A redox-regulated disulphide may form within TRAF2 and NCK-interacting protein kinase between cysteines 134 and 269. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

5d7a

Structure name

crystal structure of the kinase domain of traf2 and nck-interacting protein kinase with ncb-0846

Structure deposition date

2015-08-13

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

Q9UKE5

Residue number A

134

Residue number B

269

Peptide name

TRAF2 and NCK-interacting protein kinase

Ligandability

Cysteine 134 of TRAF2 and NCK-interacting protein kinase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.