ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

Intramolecular
Cysteine 527 and cysteine 556
A redox-regulated disulphide may form within Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase between cysteines 527 and 556.

Details

Redox score ?
80
PDB code
1fmi
Structure name
crystal structure of human class i alpha1,2-mannosidase
Structure deposition date
2000-08-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
97
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9UKM7
Residue number A
527
Residue number B
556
Peptide name
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

Ligandability

Cysteine 527 of Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 556 of Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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