F-box only protein 5
Intramolecular
Cysteine 378 and cysteine 396
Cysteine 396 and cysteine 401
Cysteine 378 and cysteine 401
Cysteine 409 and cysteine 419
Cysteine 381 and cysteine 396
Cysteine 406 and cysteine 409
Cysteine 378 and cysteine 381
Cysteine 406 and cysteine 419
Cysteine 409 and cysteine 411
Cysteine 381 and cysteine 401
More...Cysteine 411 and cysteine 419
Cysteine 406 and cysteine 411
2m6n A 17 A 35
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 378 and 396 (17 and 35 respectively in this structure).
Details
Redox score ?
83
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
7
% buried
0
Peptide accession
Q9UKT4
Residue number A
378
Residue number B
396
Peptide name
F-box only protein 5
Ligandability
Cysteine 378 of F-box only protein 5
Cysteine 396 of F-box only protein 5
2m6n A 35 A 40
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 396 and 401 (35 and 40 respectively in this structure).
Details
Redox score ?
82
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
7
% buried
0
Peptide accession
Q9UKT4
Residue number A
396
Residue number B
401
Peptide name
F-box only protein 5
Ligandability
Cysteine 396 of F-box only protein 5
Cysteine 401 of F-box only protein 5
2m6n A 17 A 40
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 378 and 401 (17 and 40 respectively in this structure).
Details
Redox score ?
81
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
8
% buried
0
Peptide accession
Q9UKT4
Residue number A
378
Residue number B
401
Peptide name
F-box only protein 5
Ligandability
Cysteine 378 of F-box only protein 5
Cysteine 401 of F-box only protein 5
2m6n A 48 A 58
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 409 and 419 (48 and 58 respectively in this structure).
Details
Redox score ?
78
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
5
Half-sphere exposure sum ?
nan
Minimum pKa ?
8
% buried
0
Peptide accession
Q9UKT4
Residue number A
409
Residue number B
419
Peptide name
F-box only protein 5
Ligandability
Cysteine 409 of F-box only protein 5
Cysteine 419 of F-box only protein 5
2m6n A 20 A 35
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 381 and 396 (20 and 35 respectively in this structure).
Details
Redox score ?
72
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
43
Minimum pKa ?
7
% buried
0
Peptide accession
Q9UKT4
Residue number A
381
Residue number B
396
Peptide name
F-box only protein 5
Ligandability
Cysteine 381 of F-box only protein 5
Cysteine 396 of F-box only protein 5
2m6n A 45 A 48
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 406 and 409 (45 and 48 respectively in this structure).
Details
Redox score ?
72
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
5
Half-sphere exposure sum ?
44
Minimum pKa ?
8
% buried
0
Peptide accession
Q9UKT4
Residue number A
406
Residue number B
409
Peptide name
F-box only protein 5
Ligandability
Cysteine 406 of F-box only protein 5
Cysteine 409 of F-box only protein 5
2m6n A 17 A 20
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 378 and 381 (17 and 20 respectively in this structure).
Details
Redox score ?
71
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
43
Minimum pKa ?
8
% buried
0
Peptide accession
Q9UKT4
Residue number A
378
Residue number B
381
Peptide name
F-box only protein 5
Ligandability
Cysteine 378 of F-box only protein 5
Cysteine 381 of F-box only protein 5
2m6n A 45 A 58
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 406 and 419 (45 and 58 respectively in this structure).
Details
Redox score ?
71
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
nan
Minimum pKa ?
8
% buried
0
Peptide accession
Q9UKT4
Residue number A
406
Residue number B
419
Peptide name
F-box only protein 5
Ligandability
Cysteine 406 of F-box only protein 5
Cysteine 419 of F-box only protein 5
2m6n A 48 A 50
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 409 and 411 (48 and 50 respectively in this structure).
Details
Redox score ?
71
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
5
Half-sphere exposure sum ?
36
Minimum pKa ?
8
% buried
0
Peptide accession
Q9UKT4
Residue number A
409
Residue number B
411
Peptide name
F-box only protein 5
Ligandability
Cysteine 409 of F-box only protein 5
Cysteine 411 of F-box only protein 5
2m6n A 20 A 40
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 381 and 401 (20 and 40 respectively in this structure).
Details
Redox score ?
70
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
33
Minimum pKa ?
8
% buried
0
Peptide accession
Q9UKT4
Residue number A
381
Residue number B
401
Peptide name
F-box only protein 5
Ligandability
Cysteine 381 of F-box only protein 5
Cysteine 401 of F-box only protein 5
2m6n A 50 A 58
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 411 and 419 (50 and 58 respectively in this structure).
Details
Redox score ?
63
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
0
Peptide accession
Q9UKT4
Residue number A
411
Residue number B
419
Peptide name
F-box only protein 5
Ligandability
Cysteine 411 of F-box only protein 5
Cysteine 419 of F-box only protein 5
2m6n A 45 A 50
A redox-regulated disulphide may form within F-box only protein 5 between cysteines 406 and 411 (45 and 50 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
2m6n
Structure name
3d solution structure of emi1 (early mitotic inhibitor 1)
Structure deposition date
2013-04-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
50
Minimum pKa ?
8
% buried
0
Peptide accession
Q9UKT4
Residue number A
406
Residue number B
411
Peptide name
F-box only protein 5
Ligandability
Cysteine 406 of F-box only protein 5
Cysteine 411 of F-box only protein 5
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