Angiopoietin-related protein 2

Intermolecular

A redox-regulated disulphide may form between two units of Angiopoietin-related protein 2 at cysteines 443 and 443 (175 and 175 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6y41

Structure name

fibrinogen-like globe domain of human angptl2

Structure deposition date

2020-02-19

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide A name

Angiopoietin-related protein 2

Peptide B name

Angiopoietin-related protein 2

Peptide A accession

Q9UKU9

Peptide B accession

Q9UKU9

Peptide A residue number

443

Peptide B residue number

443

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between two units of Angiopoietin-related protein 2 at cysteines 430 and 443 (162 and 175 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?