a tool for identifying drug-targetable redox-active disulphides

BAG family molecular chaperone regulator 5

Intramolecular

Cysteine 360 and cysteine 420

A redox-regulated disulphide may form within BAG family molecular chaperone regulator 5 between cysteines 360 and 420.

Details

Redox score ?

86

PDB code

Structure name

crystal structure of the complex between the bag5 bd5 and hsp70 nbd

Structure deposition date

2009-10-13

Thiol separation (Å)

2

Half-sphere exposure sum ?

70

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

360

Residue number B

420

Peptide name

BAG family molecular chaperone regulator 5

Ligandability

Cysteine 360 of BAG family molecular chaperone regulator 5

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 420 of BAG family molecular chaperone regulator 5

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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