Glutamate receptor ionotropic, delta-1
Intermolecular
Cysteine 80 and cysteine 80
Cysteine 351 and cysteine 351
Cysteine 80 and cysteine 351
Cysteine 96 and cysteine 96
Intramolecular
Cysteine 756 and cysteine 811
Cysteine 294 and cysteine 306
Cysteine 96 and cysteine 128
Cysteine 80 and cysteine 351
Cysteine 568 and cysteine 645
5kc9 A 80 B 80
A redox-regulated disulphide may form between two units of Glutamate receptor ionotropic, delta-1 at cysteines 80 and 80. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
5kc9
Structure name
crystal structure of the amino-terminal domain (atd) of iglur delta-1 (glud1)
Structure deposition date
2016-06-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide A name
Glutamate receptor ionotropic, delta-1
Peptide B name
Glutamate receptor ionotropic, delta-1
Peptide A accession
Q61627
Peptide B accession
Q61627
Peptide A residue number
80
Peptide B residue number
80
Ligandability
6ksp C 331 D 331
A redox-regulated disulphide may form between two units of Glutamate receptor ionotropic, delta-1 at cysteines 351 and 351 (331 and 331 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
6ksp
Structure name
rat glud1 receptor(splayed conformation) in complex with 7-cka and calcium ions
Structure deposition date
2019-08-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
73
Minimum pKa ?
11
% buried
nan
Peptide A name
Glutamate receptor ionotropic, delta-1
Peptide B name
Glutamate receptor ionotropic, delta-1
Peptide A accession
Q62640
Peptide B accession
Q62640
Peptide A residue number
351
Peptide B residue number
351
Ligandability
6ksp C 60 D 331
A redox-regulated disulphide may form between two units of Glutamate receptor ionotropic, delta-1 at cysteines 80 and 351 (60 and 331 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
6ksp
Structure name
rat glud1 receptor(splayed conformation) in complex with 7-cka and calcium ions
Structure deposition date
2019-08-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
68
Minimum pKa ?
11
% buried
nan
Peptide A name
Glutamate receptor ionotropic, delta-1
Peptide B name
Glutamate receptor ionotropic, delta-1
Peptide A accession
Q62640
Peptide B accession
Q62640
Peptide A residue number
80
Peptide B residue number
351
Ligandability
Cysteine 80 of Glutamate receptor ionotropic, delta-1
Cysteine 351 of Glutamate receptor ionotropic, delta-1
6ksp C 76 D 76
A redox-regulated disulphide may form between two units of Glutamate receptor ionotropic, delta-1 at cysteines 96 and 96 (76 and 76 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
6ksp
Structure name
rat glud1 receptor(splayed conformation) in complex with 7-cka and calcium ions
Structure deposition date
2019-08-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide A name
Glutamate receptor ionotropic, delta-1
Peptide B name
Glutamate receptor ionotropic, delta-1
Peptide A accession
Q62640
Peptide B accession
Q62640
Peptide A residue number
96
Peptide B residue number
96
Ligandability
6ksp D 736 D 791
A redox-regulated disulphide may form within Glutamate receptor ionotropic, delta-1 between cysteines 756 and 811 (736 and 791 respectively in this structure).
Details
Redox score ?
87
PDB code
6ksp
Structure name
rat glud1 receptor(splayed conformation) in complex with 7-cka and calcium ions
Structure deposition date
2019-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
35
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q62640
Residue number A
756
Residue number B
811
Peptide name
Glutamate receptor ionotropic, delta-1
Ligandability
Cysteine 756 of Glutamate receptor ionotropic, delta-1
Cysteine 811 of Glutamate receptor ionotropic, delta-1
6ksp D 274 D 286
A redox-regulated disulphide may form within Glutamate receptor ionotropic, delta-1 between cysteines 294 and 306 (274 and 286 respectively in this structure).
Details
Redox score ?
85
PDB code
6ksp
Structure name
rat glud1 receptor(splayed conformation) in complex with 7-cka and calcium ions
Structure deposition date
2019-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q62640
Residue number A
294
Residue number B
306
Peptide name
Glutamate receptor ionotropic, delta-1
Ligandability
Cysteine 294 of Glutamate receptor ionotropic, delta-1
Cysteine 306 of Glutamate receptor ionotropic, delta-1
6ksp A 76 A 108
A redox-regulated disulphide may form within Glutamate receptor ionotropic, delta-1 between cysteines 96 and 128 (76 and 108 respectively in this structure).
Details
Redox score ?
84
PDB code
6ksp
Structure name
rat glud1 receptor(splayed conformation) in complex with 7-cka and calcium ions
Structure deposition date
2019-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q62640
Residue number A
96
Residue number B
128
Peptide name
Glutamate receptor ionotropic, delta-1
Ligandability
Cysteine 96 of Glutamate receptor ionotropic, delta-1
Cysteine 128 of Glutamate receptor ionotropic, delta-1
5kc9 A 80 A 351
A redox-regulated disulphide may form within Glutamate receptor ionotropic, delta-1 between cysteines 80 and 351.
Details
Redox score ?
79
PDB code
5kc9
Structure name
crystal structure of the amino-terminal domain (atd) of iglur delta-1 (glud1)
Structure deposition date
2016-06-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q61627
Residue number A
80
Residue number B
351
Peptide name
Glutamate receptor ionotropic, delta-1
Ligandability
Cysteine 80 of Glutamate receptor ionotropic, delta-1
Cysteine 351 of Glutamate receptor ionotropic, delta-1
6ksp A 548 A 625
A redox-regulated disulphide may form within Glutamate receptor ionotropic, delta-1 between cysteines 568 and 645 (548 and 625 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
6ksp
Structure name
rat glud1 receptor(splayed conformation) in complex with 7-cka and calcium ions
Structure deposition date
2019-08-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
34
Peptide accession
Q62640
Residue number A
568
Residue number B
645
Peptide name
Glutamate receptor ionotropic, delta-1
Ligandability
Cysteine 568 of Glutamate receptor ionotropic, delta-1
Cysteine 645 of Glutamate receptor ionotropic, delta-1
If this tool was useful for finding a disulphide, please cite: