E3 ubiquitin-protein ligase HECTD1

Intramolecular

Cysteine 1893 and cysteine 1955

A redox-regulated disulphide may form within E3 ubiquitin-protein ligase HECTD1 between cysteines 1893 and 1955 (15 and 77 respectively in this structure).

Details

Redox score ?

PDB code

2lc3

Structure name

solution nmr structure of a helical bundle domain from human e3 ligase hectd1

Structure deposition date

2011-04-15

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q9ULT8

Residue number A

1893

Residue number B

1955

Peptide name

E3 ubiquitin-protein ligase HECTD1

Ligandability

Cysteine 1893 of E3 ubiquitin-protein ligase HECTD1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.