ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Phosphatidylinositol phosphatase PTPRQ

Intramolecular
Cysteine 2137 and cysteine 2145
A redox-regulated disulphide may form within Phosphatidylinositol phosphatase PTPRQ between cysteines 2137 and 2145 (2783 and 2791 respectively in this structure).

Details

Redox score ?
73
PDB code
4ikc
Structure name
crystal structure of catalytic domain of ptprq
Structure deposition date
2012-12-26
Thiol separation (Å)
6
Half-sphere exposure sum ?
nan
Minimum pKa ?
10
% buried
41
Peptide accession
Q9UMZ3
Residue number A
2137
Residue number B
2145
Peptide name
Phosphatidylinositol phosphatase PTPRQ

Ligandability

Cysteine 2137 of Phosphatidylinositol phosphatase PTPRQ

Cysteine 2145 of Phosphatidylinositol phosphatase PTPRQ

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