ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Endothelial protein C receptor

Intramolecular
Cysteine 118 and cysteine 186
A redox-regulated disulphide may form within Endothelial protein C receptor between cysteines 118 and 186 (101 and 169 respectively in this structure).

Details

Redox score ?
69
PDB code
7okv
Structure name
crystal structure of soluble epcr after exposure to the nonionic surfactant polysorbate 20
Structure deposition date
2021-05-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
38
Peptide accession
Q9UNN8
Residue number A
118
Residue number B
186
Peptide name
Endothelial protein C receptor

Ligandability

Cysteine 118 of Endothelial protein C receptor

Cysteine 186 of Endothelial protein C receptor

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