Aurora kinase C

Intramolecular

A redox-regulated disulphide may form within Aurora kinase C between cysteines 200 and 224. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6gr8

Structure name

human aurkc incenp complex bound to brd-7880

Structure deposition date

2018-06-10

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q9UQB9

Residue number A

200

Residue number B

224

Peptide name

Aurora kinase C

Ligandability

Cysteine 200 of Aurora kinase C

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.