a tool for identifying drug-targetable redox-active disulphides

Aminopeptidase NAALADL1

Intramolecular

Cysteine 296 and cysteine 313

A redox-regulated disulphide may form within Aminopeptidase NAALADL1 between cysteines 296 and 313.

Details

Redox score ?

81

PDB code

Structure name

structure of ligand-free n-acetylated-alpha-linked-acidic-dipeptidase like protein (naaladasel)

Structure deposition date

2014-06-30

Thiol separation (Å)

2

Half-sphere exposure sum ?

55

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

296

Residue number B

313

Peptide name

Aminopeptidase NAALADL1

Ligandability

Cysteine 296 of Aminopeptidase NAALADL1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 313 of Aminopeptidase NAALADL1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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