Sex comb on midleg-like protein 2
Intramolecular
Cysteine 453 and cysteine 458
Cysteine 399 and cysteine 453
Cysteine 399 and cysteine 458
Cysteine 399 and cysteine 402
Cysteine 402 and cysteine 458
Cysteine 81 and cysteine 121
Cysteine 190 and cysteine 230
Cysteine 402 and cysteine 453
2mem A 453 A 458
A redox-regulated disulphide may form within Sex comb on midleg-like protein 2 between cysteines 453 and 458.
Details
Redox score ?
69
PDB code
2mem
Structure name
solution nmr structure of sled domain of scml2
Structure deposition date
2013-09-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
65
Minimum pKa ?
12
% buried
70
Peptide accession
Q9UQR0
Residue number A
453
Residue number B
458
Peptide name
Sex comb on midleg-like protein 2
Ligandability
Cysteine 453 of Sex comb on midleg-like protein 2
Cysteine 458 of Sex comb on midleg-like protein 2
2mem A 399 A 453
A redox-regulated disulphide may form within Sex comb on midleg-like protein 2 between cysteines 399 and 453.
Details
Redox score ?
61
PDB code
2mem
Structure name
solution nmr structure of sled domain of scml2
Structure deposition date
2013-09-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
83
Minimum pKa ?
12
% buried
88
Peptide accession
Q9UQR0
Residue number A
399
Residue number B
453
Peptide name
Sex comb on midleg-like protein 2
Ligandability
Cysteine 399 of Sex comb on midleg-like protein 2
Cysteine 453 of Sex comb on midleg-like protein 2
2mem A 399 A 458
A redox-regulated disulphide may form within Sex comb on midleg-like protein 2 between cysteines 399 and 458. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
2mem
Structure name
solution nmr structure of sled domain of scml2
Structure deposition date
2013-09-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
80
Minimum pKa ?
12
% buried
81
Peptide accession
Q9UQR0
Residue number A
399
Residue number B
458
Peptide name
Sex comb on midleg-like protein 2
Ligandability
Cysteine 399 of Sex comb on midleg-like protein 2
Cysteine 458 of Sex comb on midleg-like protein 2
2mem A 399 A 402
A redox-regulated disulphide may form within Sex comb on midleg-like protein 2 between cysteines 399 and 402. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
2mem
Structure name
solution nmr structure of sled domain of scml2
Structure deposition date
2013-09-24
Thiol separation (Å)
7
Half-sphere exposure sum ?
81
Minimum pKa ?
11
% buried
73
Peptide accession
Q9UQR0
Residue number A
399
Residue number B
402
Peptide name
Sex comb on midleg-like protein 2
Ligandability
Cysteine 399 of Sex comb on midleg-like protein 2
Cysteine 402 of Sex comb on midleg-like protein 2
2mem A 402 A 458
A redox-regulated disulphide may form within Sex comb on midleg-like protein 2 between cysteines 402 and 458. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
2mem
Structure name
solution nmr structure of sled domain of scml2
Structure deposition date
2013-09-24
Thiol separation (Å)
8
Half-sphere exposure sum ?
63
Minimum pKa ?
11
% buried
55
Peptide accession
Q9UQR0
Residue number A
402
Residue number B
458
Peptide name
Sex comb on midleg-like protein 2
Ligandability
Cysteine 402 of Sex comb on midleg-like protein 2
Cysteine 458 of Sex comb on midleg-like protein 2
1oi1 A 81 A 121
A redox-regulated disulphide may form within Sex comb on midleg-like protein 2 between cysteines 81 and 121. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
1oi1
Structure name
crystal structure of the mbt domains of human scml2
Structure deposition date
2003-06-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
11
% buried
36
Peptide accession
Q9UQR0
Residue number A
81
Residue number B
121
Peptide name
Sex comb on midleg-like protein 2
Ligandability
Cysteine 81 of Sex comb on midleg-like protein 2
Cysteine 121 of Sex comb on midleg-like protein 2
2vyt B 190 B 230
A redox-regulated disulphide may form within Sex comb on midleg-like protein 2 between cysteines 190 and 230. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
2vyt
Structure name
the mbt repeats of human scml2 bind to peptides containing mono methylated lysine
Structure deposition date
2008-07-28
Thiol separation (Å)
9
Half-sphere exposure sum ?
72
Minimum pKa ?
11
% buried
74
Peptide accession
Q9UQR0
Residue number A
190
Residue number B
230
Peptide name
Sex comb on midleg-like protein 2
Ligandability
Cysteine 190 of Sex comb on midleg-like protein 2
Cysteine 230 of Sex comb on midleg-like protein 2
2mem A 402 A 453
A redox-regulated disulphide may form within Sex comb on midleg-like protein 2 between cysteines 402 and 453. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
2mem
Structure name
solution nmr structure of sled domain of scml2
Structure deposition date
2013-09-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
11
% buried
62
Peptide accession
Q9UQR0
Residue number A
402
Residue number B
453
Peptide name
Sex comb on midleg-like protein 2
Ligandability
Cysteine 402 of Sex comb on midleg-like protein 2
Cysteine 453 of Sex comb on midleg-like protein 2
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