ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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RAC-gamma serine/threonine-protein kinase

Intramolecular
Cysteine 59 and cysteine 76
A redox-regulated disulphide may form within RAC-gamma serine/threonine-protein kinase between cysteines 59 and 76.

Details

Redox score ?
64
PDB code
2x18
Structure name
the crystal structure of the ph domain of human akt3 protein kinase
Structure deposition date
2009-12-22
Thiol separation (Å)
5
Half-sphere exposure sum ?
60
Minimum pKa ?
11
% buried
74
Peptide accession
Q9Y243
Residue number A
59
Residue number B
76
Peptide name
RAC-gamma serine/threonine-protein kinase

Ligandability

Cysteine 59 of RAC-gamma serine/threonine-protein kinase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 76 of RAC-gamma serine/threonine-protein kinase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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