a tool for identifying drug-targetable redox-active disulphides

Choline/ethanolamine kinase

Intramolecular

Cysteine 53 and cysteine 85

A redox-regulated disulphide may form within Choline/ethanolamine kinase between cysteines 53 and 85.

Details

Redox score ?

72

PDB code

Structure name

crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide

Structure deposition date

2008-11-29

Thiol separation (Å)

4

Half-sphere exposure sum ?

78

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

53

Residue number B

85

Peptide name

Choline/ethanolamine kinase

Ligandability

Cysteine 53 of Choline/ethanolamine kinase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 85 of Choline/ethanolamine kinase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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