ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

RuvB-like 1

Intermolecular
Cysteine 206 and cysteine 339 of Actin-related protein 6
A redox-regulated disulphide may form between cysteine 206 of RuvB-like 1 and cysteine 339 of Actin-related protein 6. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
6igm
Structure name
cryo-em structure of human srcap complex
Structure deposition date
2018-09-25
Thiol separation (Å)
8
Half-sphere exposure sum ?
57
Minimum pKa ?
11
% buried
59
Peptide A name
RuvB-like 1
Peptide B name
Actin-related protein 6
Peptide A accession
Q9Y265
Peptide B accession
Q9GZN1
Peptide A residue number
206
Peptide B residue number
339

Ligandability

Cysteine 206 of RuvB-like 1

Cysteine 339 of Actin-related protein 6

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