ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Phosphatidylinositide phosphatase SAC2

Intermolecular
Cysteine 725 and cysteine 725
A redox-regulated disulphide may form between two units of Phosphatidylinositide phosphatase SAC2 at cysteines 725 and 725 (134 and 134 respectively in this structure).

Details

Redox score ?
82
PDB code
4xuu
Structure name
the hsac2 domain from human phosphoinositide phosphatase sac2
Structure deposition date
2015-01-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide A name
Phosphatidylinositide phosphatase SAC2
Peptide B name
Phosphatidylinositide phosphatase SAC2
Peptide A accession
Q9Y2H2
Peptide B accession
Q9Y2H2
Peptide A residue number
725
Peptide B residue number
725

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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