a tool for identifying drug-targetable redox-active disulphides

28S ribosomal protein S28, mitochondrial

Intramolecular

Cysteine 122 and cysteine 124

A redox-regulated disulphide may form within 28S ribosomal protein S28, mitochondrial between cysteines 122 and 124.

Details

Redox score ?

74

PDB code

Structure name

human mitochondrial small subunit assembly intermediate (state b)

Structure deposition date

2022-05-13

Thiol separation (Å)

4

Half-sphere exposure sum ?

73

Minimum pK_a ?

8

% buried

82

Peptide accession

Residue number A

122

Residue number B

124

Peptide name

28S ribosomal protein S28, mitochondrial

Ligandability

Cysteine 122 of 28S ribosomal protein S28, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 124 of 28S ribosomal protein S28, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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