ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Zinc finger and BTB domain-containing protein 32

Intramolecular
Cysteine 380 and cysteine 383
Cysteine 407 and cysteine 410
Cysteine 352 and cysteine 355
Cysteine 407 and cysteine 414
Cysteine 410 and cysteine 414
A redox-regulated disulphide may form within Zinc finger and BTB domain-containing protein 32 between cysteines 380 and 383 (34 and 37 respectively in this structure).

Details

Redox score ?
95
PDB code
2kvh
Structure name
structure of the three-cys2his2 domain of mouse testis zinc finger protein
Structure deposition date
2010-03-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
35
Minimum pKa ?
6
% buried
0
Peptide accession
Q9JKD9
Residue number A
380
Residue number B
383
Peptide name
Zinc finger and BTB domain-containing protein 32

Ligandability

Cysteine 380 of Zinc finger and BTB domain-containing protein 32

Cysteine 383 of Zinc finger and BTB domain-containing protein 32

A redox-regulated disulphide may form within Zinc finger and BTB domain-containing protein 32 between cysteines 407 and 410 (61 and 64 respectively in this structure).

Details

Redox score ?
89
PDB code
2kvg
Structure name
structure of the three-cys2his2 domain of mouse testis zinc finger protein
Structure deposition date
2010-03-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
35
Minimum pKa ?
7
% buried
0
Peptide accession
Q9JKD9
Residue number A
407
Residue number B
410
Peptide name
Zinc finger and BTB domain-containing protein 32

Ligandability

Cysteine 407 of Zinc finger and BTB domain-containing protein 32

Cysteine 410 of Zinc finger and BTB domain-containing protein 32

A redox-regulated disulphide may form within Zinc finger and BTB domain-containing protein 32 between cysteines 352 and 355 (6 and 9 respectively in this structure).

Details

Redox score ?
83
PDB code
2kvf
Structure name
structure of the three-cys2his2 domain of mouse testis zinc finger protein
Structure deposition date
2010-03-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
37
Minimum pKa ?
8
% buried
0
Peptide accession
Q9JKD9
Residue number A
352
Residue number B
355
Peptide name
Zinc finger and BTB domain-containing protein 32

Ligandability

Cysteine 352 of Zinc finger and BTB domain-containing protein 32

Cysteine 355 of Zinc finger and BTB domain-containing protein 32

A redox-regulated disulphide may form within Zinc finger and BTB domain-containing protein 32 between cysteines 407 and 414 (61 and 68 respectively in this structure).

Details

Redox score ?
73
PDB code
2kvg
Structure name
structure of the three-cys2his2 domain of mouse testis zinc finger protein
Structure deposition date
2010-03-15
Thiol separation (Å)
6
Half-sphere exposure sum ?
40
Minimum pKa ?
7
% buried
0
Peptide accession
Q9JKD9
Residue number A
407
Residue number B
414
Peptide name
Zinc finger and BTB domain-containing protein 32

Ligandability

Cysteine 407 of Zinc finger and BTB domain-containing protein 32

Cysteine 414 of Zinc finger and BTB domain-containing protein 32

A redox-regulated disulphide may form within Zinc finger and BTB domain-containing protein 32 between cysteines 410 and 414 (64 and 68 respectively in this structure).

Details

Redox score ?
61
PDB code
2kvg
Structure name
structure of the three-cys2his2 domain of mouse testis zinc finger protein
Structure deposition date
2010-03-15
Thiol separation (Å)
7
Half-sphere exposure sum ?
33
Minimum pKa ?
9
% buried
0
Peptide accession
Q9JKD9
Residue number A
410
Residue number B
414
Peptide name
Zinc finger and BTB domain-containing protein 32

Ligandability

Cysteine 410 of Zinc finger and BTB domain-containing protein 32

Cysteine 414 of Zinc finger and BTB domain-containing protein 32

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