Protein MEMO1
Intermolecular
Cysteine 7 and cysteine 7
Intramolecular
Cysteine 55 and cysteine 58
Cysteine 191 and cysteine 279
Cysteine 191 and cysteine 244
7m8h A 7 C 7
A redox-regulated disulphide may form between two units of Protein MEMO1 at cysteines 7 and 7. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
7m8h
Structure name
structure of memo1 c244s metal binding site mutant at 1
Structure deposition date
2021-03-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
58
Minimum pKa ?
9
% buried
46
Peptide A name
Protein MEMO1
Peptide B name
Protein MEMO1
Peptide A accession
Q9Y316
Peptide B accession
Q9Y316
Peptide A residue number
7
Peptide B residue number
7
Ligandability
7l5c D 55 D 58
A redox-regulated disulphide may form within Protein MEMO1 between cysteines 55 and 58. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
7l5c
Structure name
structure of copper bound memo1
Structure deposition date
2020-12-21
Thiol separation (Å)
7
Half-sphere exposure sum ?
74
Minimum pKa ?
12
% buried
94
Peptide accession
Q9Y316
Residue number A
55
Residue number B
58
Peptide name
Protein MEMO1
Ligandability
Cysteine 55 of Protein MEMO1
Cysteine 58 of Protein MEMO1
7kq8 D 191 D 279
A redox-regulated disulphide may form within Protein MEMO1 between cysteines 191 and 279. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7kq8
Structure name
structure of iron bound memo1
Structure deposition date
2020-11-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
11
% buried
73
Peptide accession
Q9Y316
Residue number A
191
Residue number B
279
Peptide name
Protein MEMO1
Ligandability
Cysteine 191 of Protein MEMO1
Cysteine 279 of Protein MEMO1
3bcz C 191 C 244
A redox-regulated disulphide may form within Protein MEMO1 between cysteines 191 and 244. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
22
PDB code
3bcz
Structure name
crystal structure of memo
Structure deposition date
2007-11-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
82
Minimum pKa ?
13
% buried
98
Peptide accession
Q9Y316
Residue number A
191
Residue number B
244
Peptide name
Protein MEMO1
Ligandability
Cysteine 191 of Protein MEMO1
Cysteine 244 of Protein MEMO1
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