ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

RNA-binding motif protein, X-linked 2

Intramolecular
Cysteine 83 and cysteine 136
A redox-regulated disulphide may form within RNA-binding motif protein, X-linked 2 between cysteines 83 and 136. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
32
PDB code
7dvq
Structure name
cryo-em structure of the activated human minor spliceosome (minor bact complex)
Structure deposition date
2021-01-14
Thiol separation (Å)
9
Half-sphere exposure sum ?
81
Minimum pKa ?
11
% buried
92
Peptide accession
Q9Y388
Residue number A
83
Residue number B
136
Peptide name
RNA-binding motif protein, X-linked 2

Ligandability

Cysteine 83 of RNA-binding motif protein, X-linked 2

Cysteine 136 of RNA-binding motif protein, X-linked 2

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