ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

28S ribosomal protein S2, mitochondrial

Intramolecular
Cysteine 162 and cysteine 250
A redox-regulated disulphide may form within 28S ribosomal protein S2, mitochondrial between cysteines 162 and 250. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
32
PDB code
8csu
Structure name
human mitochondrial small subunit assembly intermediate (state c*)
Structure deposition date
2022-05-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
12
% buried
96
Peptide accession
Q9Y399
Residue number A
162
Residue number B
250
Peptide name
28S ribosomal protein S2, mitochondrial

Ligandability

Cysteine 162 of 28S ribosomal protein S2, mitochondrial

Cysteine 250 of 28S ribosomal protein S2, mitochondrial

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