ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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MOB-like protein phocein

Intramolecular
Cysteine 110 and cysteine 119
Cysteine 92 and cysteine 97
A redox-regulated disulphide may form within MOB-like protein phocein between cysteines 110 and 119.

Details

Redox score ?
88
PDB code
7k36
Structure name
cryo-em structure of stripak complex
Structure deposition date
2020-09-10
Thiol separation (Å)
3
Half-sphere exposure sum ?
66
Minimum pKa ?
5
% buried
nan
Peptide accession
Q9Y3A3
Residue number A
110
Residue number B
119
Peptide name
MOB-like protein phocein

Ligandability

Cysteine 110 of MOB-like protein phocein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 119 of MOB-like protein phocein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within MOB-like protein phocein between cysteines 92 and 97.

Details

Redox score ?
84
PDB code
7k36
Structure name
cryo-em structure of stripak complex
Structure deposition date
2020-09-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
40
Peptide accession
Q9Y3A3
Residue number A
92
Residue number B
97
Peptide name
MOB-like protein phocein

Ligandability

Cysteine 92 of MOB-like protein phocein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 97 of MOB-like protein phocein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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