ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Exosome complex component CSL4

Intramolecular
Cysteine 8 and cysteine 40
A redox-regulated disulphide may form within Exosome complex component CSL4 between cysteines 8 and 40. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
55
PDB code
2nn6
Structure name
structure of the human rna exosome composed of rrp41, rrp45, rrp46, rrp43, mtr3, rrp42, csl4, rrp4, and rrp40
Structure deposition date
2006-10-23
Thiol separation (Å)
6
Half-sphere exposure sum ?
72
Minimum pKa ?
10
% buried
41
Peptide accession
Q9Y3B2
Residue number A
8
Residue number B
40
Peptide name
Exosome complex component CSL4

Ligandability

Cysteine 8 of Exosome complex component CSL4

Cysteine 40 of Exosome complex component CSL4

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