28S ribosomal protein S18c, mitochondrial
Intermolecular
Cysteine 105 of 28S ribosomal protein S6, mitochondrial and cysteine 69 L
Cysteine 105 of 28S ribosomal protein S6, mitochondrial and cysteine 101 L
Cysteine 105 of 28S ribosomal protein S6, mitochondrial and cysteine 66 L
Intramolecular
Cysteine 65 and cysteine 100
Cysteine 65 and cysteine 68
Cysteine 68 and cysteine 100
Cysteine 90 and cysteine 136
6neq F 105 R 69
A redox-regulated disulphide may form between cysteine 105 of 28S ribosomal protein S6, mitochondrial and cysteine 69 of 28S ribosomal protein S18c, mitochondrial.
Details
Redox score ?
74
PDB code
6neq
Structure name
structure of human mitochondrial translation initiation factor 3 bound to the small ribosomal subunit-class-ii
Structure deposition date
2018-12-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
14
Peptide A name
28S ribosomal protein S6, mitochondrial
Peptide B name
28S ribosomal protein S18c, mitochondrial
Peptide A accession
P82931
Peptide B accession
P82917
Peptide A residue number
105
Peptide B residue number
69
Ligandability
Cysteine 105 of 28S ribosomal protein S6, mitochondrial
Cysteine 69 of 28S ribosomal protein S18c, mitochondrial
6nf8 F 105 R 101
A redox-regulated disulphide may form between cysteine 105 of 28S ribosomal protein S6, mitochondrial and cysteine 101 of 28S ribosomal protein S18c, mitochondrial.
Details
Redox score ?
70
PDB code
6nf8
Structure name
structure of human mitochondrial translation initiation factor 3 bound to the small ribosomal subunit -class i
Structure deposition date
2018-12-19
Thiol separation (Å)
6
Half-sphere exposure sum ?
51
Minimum pKa ?
9
% buried
28
Peptide A name
28S ribosomal protein S6, mitochondrial
Peptide B name
28S ribosomal protein S18c, mitochondrial
Peptide A accession
P82931
Peptide B accession
P82917
Peptide A residue number
105
Peptide B residue number
101
Ligandability
Cysteine 105 of 28S ribosomal protein S6, mitochondrial
Cysteine 101 of 28S ribosomal protein S18c, mitochondrial
6neq F 105 R 66
A redox-regulated disulphide may form between cysteine 105 of 28S ribosomal protein S6, mitochondrial and cysteine 66 of 28S ribosomal protein S18c, mitochondrial.
Details
Redox score ?
64
PDB code
6neq
Structure name
structure of human mitochondrial translation initiation factor 3 bound to the small ribosomal subunit-class-ii
Structure deposition date
2018-12-18
Thiol separation (Å)
6
Half-sphere exposure sum ?
51
Minimum pKa ?
9
% buried
34
Peptide A name
28S ribosomal protein S6, mitochondrial
Peptide B name
28S ribosomal protein S18c, mitochondrial
Peptide A accession
P82931
Peptide B accession
P82917
Peptide A residue number
105
Peptide B residue number
66
Ligandability
Cysteine 105 of 28S ribosomal protein S6, mitochondrial
Cysteine 66 of 28S ribosomal protein S18c, mitochondrial
8csq P 65 P 100
A redox-regulated disulphide may form within 28S ribosomal protein S18c, mitochondrial between cysteines 65 and 100.
Details
Redox score ?
78
PDB code
8csq
Structure name
human mitochondrial small subunit assembly intermediate (state b)
Structure deposition date
2022-05-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
8
% buried
26
Peptide accession
Q9Y3D5
Residue number A
65
Residue number B
100
Peptide name
28S ribosomal protein S18c, mitochondrial
Ligandability
Cysteine 65 of 28S ribosomal protein S18c, mitochondrial
Cysteine 100 of 28S ribosomal protein S18c, mitochondrial
8csu P 65 P 68
A redox-regulated disulphide may form within 28S ribosomal protein S18c, mitochondrial between cysteines 65 and 68.
Details
Redox score ?
68
PDB code
8csu
Structure name
human mitochondrial small subunit assembly intermediate (state c*)
Structure deposition date
2022-05-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
59
Minimum pKa ?
10
% buried
26
Peptide accession
Q9Y3D5
Residue number A
65
Residue number B
68
Peptide name
28S ribosomal protein S18c, mitochondrial
Ligandability
Cysteine 65 of 28S ribosomal protein S18c, mitochondrial
Cysteine 68 of 28S ribosomal protein S18c, mitochondrial
8csr P 68 P 100
A redox-regulated disulphide may form within 28S ribosomal protein S18c, mitochondrial between cysteines 68 and 100. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
8csr
Structure name
human mitochondrial small subunit assembly intermediate (state c)
Structure deposition date
2022-05-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
57
Minimum pKa ?
9
% buried
21
Peptide accession
Q9Y3D5
Residue number A
68
Residue number B
100
Peptide name
28S ribosomal protein S18c, mitochondrial
Ligandability
Cysteine 68 of 28S ribosomal protein S18c, mitochondrial
Cysteine 100 of 28S ribosomal protein S18c, mitochondrial
8css P 90 P 136
A redox-regulated disulphide may form within 28S ribosomal protein S18c, mitochondrial between cysteines 90 and 136. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
30
PDB code
8css
Structure name
human mitochondrial small subunit assembly intermediate (state d)
Structure deposition date
2022-05-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
58
Minimum pKa ?
12
% buried
95
Peptide accession
Q9Y3D5
Residue number A
90
Residue number B
136
Peptide name
28S ribosomal protein S18c, mitochondrial
Ligandability
Cysteine 90 of 28S ribosomal protein S18c, mitochondrial
Cysteine 136 of 28S ribosomal protein S18c, mitochondrial
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