ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Plexin-D1

Intramolecular
Cysteine 1402 and cysteine 1921
Cysteine 1565 and cysteine 1592 L
A redox-regulated disulphide may form within Plexin-D1 between cysteines 1402 and 1921.

Details

Redox score ?
88
PDB code
5v6r
Structure name
structure of plexin d1 intracellular domain
Structure deposition date
2017-03-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
38
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q3UH93
Residue number A
1402
Residue number B
1921
Peptide name
Plexin-D1

Ligandability

Cysteine 1402 of Plexin-D1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1921 of Plexin-D1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Plexin-D1 between cysteines 1565 and 1592.

Details

Redox score ?
67
PDB code
5v6t
Structure name
the plexin d1 intracellular region in complex with gipc1
Structure deposition date
2017-03-17
Thiol separation (Å)
6
Half-sphere exposure sum ?
42
Minimum pKa ?
9
% buried
20
Peptide accession
Q3UH93
Residue number A
1565
Residue number B
1592
Peptide name
Plexin-D1

Ligandability

Cysteine 1565 of Plexin-D1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1592 of Plexin-D1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: