FERM, ARHGEF and pleckstrin domain-containing protein 1

Intramolecular

A redox-regulated disulphide may form within FERM, ARHGEF and pleckstrin domain-containing protein 1 between cysteines 665 and 674. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4h6y

Structure name

crystal structure of the dh-ph-ph domain of farp1

Structure deposition date

2012-09-19

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q9Y4F1

Residue number A

665

Residue number B

674

Peptide name

FERM, ARHGEF and pleckstrin domain-containing protein 1

Ligandability

Cysteine 665 of FERM, ARHGEF and pleckstrin domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.