ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

TOG array regulator of axonemal microtubules protein 1

Intramolecular
Cysteine 493 and cysteine 495
A redox-regulated disulphide may form within TOG array regulator of axonemal microtubules protein 1 between cysteines 493 and 495. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
26
PDB code
5dn7
Structure name
crescerin uses a tog domain array to regulate microtubules in the primary cilium
Structure deposition date
2015-09-09
Thiol separation (Å)
10
Half-sphere exposure sum ?
84
Minimum pKa ?
11
% buried
90
Peptide accession
Q6A070
Residue number A
493
Residue number B
495
Peptide name
TOG array regulator of axonemal microtubules protein 1

Ligandability

Cysteine 493 of TOG array regulator of axonemal microtubules protein 1

Cysteine 495 of TOG array regulator of axonemal microtubules protein 1

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