a tool for identifying drug-targetable redox-active disulphides

Talin-2

Intramolecular

Cysteine 9 and cysteine 13

A redox-regulated disulphide may form within Talin-2 between cysteines 9 and 13.

Details

Redox score ?

85

PDB code

Structure name

human talin2 residues 1-403

Structure deposition date

2019-08-26

Thiol separation (Å)

2

Half-sphere exposure sum ?

47

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

9

Residue number B

13

Peptide name

Talin-2

Ligandability

Cysteine 9 of Talin-2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 13 of Talin-2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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