ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

ADP-ribose glycohydrolase OARD1

Intramolecular
Cysteine 33 and cysteine 122
A redox-regulated disulphide may form within ADP-ribose glycohydrolase OARD1 between cysteines 33 and 122. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
39
PDB code
4j5q
Structure name
targ1 (c6orf130), terminal adp-ribose glycohydrolase 1, apo structure
Structure deposition date
2013-02-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
77
Minimum pKa ?
11
% buried
68
Peptide accession
Q9Y530
Residue number A
33
Residue number B
122
Peptide name
ADP-ribose glycohydrolase OARD1

Ligandability

Cysteine 33 of ADP-ribose glycohydrolase OARD1

Cysteine 122 of ADP-ribose glycohydrolase OARD1

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