ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Intraflagellar transport protein 25 homolog

Intramolecular
Cysteine 7 and cysteine 52
A redox-regulated disulphide may form within Intraflagellar transport protein 25 homolog between cysteines 7 and 52. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
29
PDB code
1xpw
Structure name
solution nmr structure of human protein hspco34
Structure deposition date
2004-10-09
Thiol separation (Å)
10
Half-sphere exposure sum ?
78
Minimum pKa ?
10
% buried
70
Peptide accession
Q9Y547
Residue number A
7
Residue number B
52
Peptide name
Intraflagellar transport protein 25 homolog

Ligandability

Cysteine 7 of Intraflagellar transport protein 25 homolog

Cysteine 52 of Intraflagellar transport protein 25 homolog

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