ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Angiopoietin-related protein 3

Intramolecular
Cysteine 394 and cysteine 408
Cysteine 246 and cysteine 274
A redox-regulated disulphide may form within Angiopoietin-related protein 3 between cysteines 394 and 408.

Details

Redox score ?
86
PDB code
6eua
Structure name
the fibrinogen-like domain of human angptl3
Structure deposition date
2017-10-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5C1
Residue number A
394
Residue number B
408
Peptide name
Angiopoietin-related protein 3

Ligandability

Cysteine 394 of Angiopoietin-related protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 408 of Angiopoietin-related protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Angiopoietin-related protein 3 between cysteines 246 and 274.

Details

Redox score ?
81
PDB code
6eua
Structure name
the fibrinogen-like domain of human angptl3
Structure deposition date
2017-10-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5C1
Residue number A
246
Residue number B
274
Peptide name
Angiopoietin-related protein 3

Ligandability

Cysteine 246 of Angiopoietin-related protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 274 of Angiopoietin-related protein 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: