a tool for identifying drug-targetable redox-active disulphides

Protocadherin gamma-B3

Intramolecular

Cysteine 96 and cysteine 102

A redox-regulated disulphide may form within Protocadherin gamma-B3 between cysteines 96 and 102 (66 and 72 respectively in this structure).

Details

Redox score ?

86

PDB code

Structure name

structure of human clustered protocadherin gamma b3 ec1-4

Structure deposition date

2016-05-30

Thiol separation (Å)

2

Half-sphere exposure sum ?

51

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

96

Residue number B

102

Peptide name

Protocadherin gamma-B3

Ligandability

Cysteine 96 of Protocadherin gamma-B3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 102 of Protocadherin gamma-B3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: