ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Olfactory receptor 51B2

Intramolecular
Cysteine 157 and cysteine 35
Cysteine 187 and cysteine 152
Cysteine 187 and cysteine 157
A redox-regulated disulphide may form within Olfactory receptor 51B2 between cysteines 157 and 35 (157 and 189 respectively in this structure).

Details

Redox score ?
65
PDB code
6lbg
Structure name
structure of or51b2 bound fem1c
Structure deposition date
2019-11-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
10
% buried
100
Peptide accession
Q9Y5P1
Residue number A
157
Residue number B
35
Peptide name
Olfactory receptor 51B2

Ligandability

Cysteine 157 of Olfactory receptor 51B2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 35 of Olfactory receptor 51B2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 157 in protein A could not be asigned to a Uniprot residue.
A redox-regulated disulphide may form within Olfactory receptor 51B2 between cysteines 187 and 152 (124 and 152 respectively in this structure).

Details

Redox score ?
nan
PDB code
6lbg
Structure name
structure of or51b2 bound fem1c
Structure deposition date
2019-11-14
Thiol separation (Å)
5
Half-sphere exposure sum ?
100
Minimum pKa ?
8
% buried
100
Peptide accession
Q9Y5P1
Residue number A
187
Residue number B
152
Peptide name
Olfactory receptor 51B2

Ligandability

Cysteine 187 of Olfactory receptor 51B2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 152 of Olfactory receptor 51B2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 152 in protein B could not be asigned to a Uniprot residue.
A redox-regulated disulphide may form within Olfactory receptor 51B2 between cysteines 187 and 157 (124 and 157 respectively in this structure).

Details

Redox score ?
nan
PDB code
6lbg
Structure name
structure of or51b2 bound fem1c
Structure deposition date
2019-11-14
Thiol separation (Å)
10
Half-sphere exposure sum ?
90
Minimum pKa ?
10
% buried
100
Peptide accession
Q9Y5P1
Residue number A
187
Residue number B
157
Peptide name
Olfactory receptor 51B2

Ligandability

Cysteine 187 of Olfactory receptor 51B2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 157 of Olfactory receptor 51B2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 157 in protein B could not be asigned to a Uniprot residue.
If this tool was useful for finding a disulphide, please cite: