Tumor necrosis factor receptor superfamily member 18
Intramolecular
Cysteine 50 and cysteine 72
Cysteine 134 and cysteine 153
Cysteine 115 and cysteine 128
Cysteine 94 and cysteine 112
Cysteine 45 and cysteine 60
Cysteine 74 and cysteine 89
Cysteine 29 and cysteine 44
Cysteine 81 and cysteine 86
Cysteine 44 and cysteine 45
Cysteine 29 and cysteine 45
More...Cysteine 74 and cysteine 86
Cysteine 72 and cysteine 86
Cysteine 29 and cysteine 60
Cysteine 86 and cysteine 89
Cysteine 50 and cysteine 86
Cysteine 74 and cysteine 81
Cysteine 44 and cysteine 60
Cysteine 72 and cysteine 81
Cysteine 45 and cysteine 74
Cysteine 81 and cysteine 89
Cysteine 49 and cysteine 50
Cysteine 50 and cysteine 81
Cysteine 29 and cysteine 77
Cysteine 29 and cysteine 74
Cysteine 72 and cysteine 74
Cysteine 50 and cysteine 89
Cysteine 50 and cysteine 74
Cysteine 29 and cysteine 62
Cysteine 45 and cysteine 69
Cysteine 29 and cysteine 69
Cysteine 94 and cysteine 128
Cysteine 72 and cysteine 85
Cysteine 72 and cysteine 89
Cysteine 49 and cysteine 72
Cysteine 94 and cysteine 115
Cysteine 45 and cysteine 77
Cysteine 85 and cysteine 86
Cysteine 44 and cysteine 69
Cysteine 112 and cysteine 128
Cysteine 112 and cysteine 115
7khd D 50 D 72
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 50 and 72.
Details
Redox score ?
90
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
38
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
50
Residue number B
72
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 50 of Tumor necrosis factor receptor superfamily member 18
Cysteine 72 of Tumor necrosis factor receptor superfamily member 18
7khd C 134 C 153
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 134 and 153.
Details
Redox score ?
88
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
134
Residue number B
153
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 134 of Tumor necrosis factor receptor superfamily member 18
Cysteine 153 of Tumor necrosis factor receptor superfamily member 18
7khd D 115 D 128
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 115 and 128.
Details
Redox score ?
88
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
115
Residue number B
128
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 115 of Tumor necrosis factor receptor superfamily member 18
Cysteine 128 of Tumor necrosis factor receptor superfamily member 18
7khd C 94 C 112
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 94 and 112.
Details
Redox score ?
87
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
94
Residue number B
112
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 94 of Tumor necrosis factor receptor superfamily member 18
Cysteine 112 of Tumor necrosis factor receptor superfamily member 18
7e57 C 45 C 60
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 45 and 60.
Details
Redox score ?
86
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
45
Residue number B
60
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 45 of Tumor necrosis factor receptor superfamily member 18
Cysteine 60 of Tumor necrosis factor receptor superfamily member 18
7khd D 74 D 89
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 74 and 89.
Details
Redox score ?
86
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
74
Residue number B
89
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 74 of Tumor necrosis factor receptor superfamily member 18
Cysteine 89 of Tumor necrosis factor receptor superfamily member 18
7e57 C 29 C 44
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 29 and 44.
Details
Redox score ?
84
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
29
Residue number B
44
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 29 of Tumor necrosis factor receptor superfamily member 18
Cysteine 44 of Tumor necrosis factor receptor superfamily member 18
7khd D 81 D 86
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 81 and 86.
Details
Redox score ?
83
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
81
Residue number B
86
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 81 of Tumor necrosis factor receptor superfamily member 18
Cysteine 86 of Tumor necrosis factor receptor superfamily member 18
7e57 D 44 D 45
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 44 and 45.
Details
Redox score ?
80
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
35
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
44
Residue number B
45
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 44 of Tumor necrosis factor receptor superfamily member 18
Cysteine 45 of Tumor necrosis factor receptor superfamily member 18
7e57 D 29 D 45
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 29 and 45.
Details
Redox score ?
80
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
29
Residue number B
45
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 29 of Tumor necrosis factor receptor superfamily member 18
Cysteine 45 of Tumor necrosis factor receptor superfamily member 18
7law R 74 R 86
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 74 and 86.
Details
Redox score ?
76
PDB code
7law
Structure name
crystal structure of gitr complex with gitr-l
Structure deposition date
2021-01-07
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
74
Residue number B
86
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 74 of Tumor necrosis factor receptor superfamily member 18
Cysteine 86 of Tumor necrosis factor receptor superfamily member 18
7khd D 72 D 86
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 72 and 86.
Details
Redox score ?
74
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
5
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
72
Residue number B
86
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 72 of Tumor necrosis factor receptor superfamily member 18
Cysteine 86 of Tumor necrosis factor receptor superfamily member 18
7e57 D 29 D 60
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 29 and 60.
Details
Redox score ?
74
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
29
Residue number B
60
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 29 of Tumor necrosis factor receptor superfamily member 18
Cysteine 60 of Tumor necrosis factor receptor superfamily member 18
7law S 86 S 89
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 86 and 89.
Details
Redox score ?
73
PDB code
7law
Structure name
crystal structure of gitr complex with gitr-l
Structure deposition date
2021-01-07
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
86
Residue number B
89
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 86 of Tumor necrosis factor receptor superfamily member 18
Cysteine 89 of Tumor necrosis factor receptor superfamily member 18
7khd D 50 D 86
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 50 and 86.
Details
Redox score ?
70
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
5
Half-sphere exposure sum ?
41
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
50
Residue number B
86
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 50 of Tumor necrosis factor receptor superfamily member 18
Cysteine 86 of Tumor necrosis factor receptor superfamily member 18
7khd C 74 C 81
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 74 and 81.
Details
Redox score ?
70
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
74
Residue number B
81
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 74 of Tumor necrosis factor receptor superfamily member 18
Cysteine 81 of Tumor necrosis factor receptor superfamily member 18
7e57 C 44 C 60
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 44 and 60.
Details
Redox score ?
66
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
6
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
44
Residue number B
60
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 44 of Tumor necrosis factor receptor superfamily member 18
Cysteine 60 of Tumor necrosis factor receptor superfamily member 18
7khd C 72 C 81
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 72 and 81.
Details
Redox score ?
63
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
6
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
72
Residue number B
81
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 72 of Tumor necrosis factor receptor superfamily member 18
Cysteine 81 of Tumor necrosis factor receptor superfamily member 18
7e57 C 45 C 74
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 45 and 74.
Details
Redox score ?
62
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
6
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
45
Residue number B
74
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 45 of Tumor necrosis factor receptor superfamily member 18
Cysteine 74 of Tumor necrosis factor receptor superfamily member 18
7khd D 81 D 89
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 81 and 89.
Details
Redox score ?
61
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
6
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
81
Residue number B
89
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 81 of Tumor necrosis factor receptor superfamily member 18
Cysteine 89 of Tumor necrosis factor receptor superfamily member 18
7khd C 49 C 50
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 49 and 50. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
7
Half-sphere exposure sum ?
38
Minimum pKa ?
9
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
49
Residue number B
50
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 49 of Tumor necrosis factor receptor superfamily member 18
Cysteine 50 of Tumor necrosis factor receptor superfamily member 18
7khd C 50 C 81
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 50 and 81. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
7
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
50
Residue number B
81
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 50 of Tumor necrosis factor receptor superfamily member 18
Cysteine 81 of Tumor necrosis factor receptor superfamily member 18
7e57 C 29 C 77
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 29 and 77. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
7
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
29
Residue number B
77
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 29 of Tumor necrosis factor receptor superfamily member 18
Cysteine 77 of Tumor necrosis factor receptor superfamily member 18
7e57 C 29 C 74
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 29 and 74. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
7
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
29
Residue number B
74
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 29 of Tumor necrosis factor receptor superfamily member 18
Cysteine 74 of Tumor necrosis factor receptor superfamily member 18
7khd C 72 C 74
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 72 and 74. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
8
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
72
Residue number B
74
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 72 of Tumor necrosis factor receptor superfamily member 18
Cysteine 74 of Tumor necrosis factor receptor superfamily member 18
7khd D 50 D 89
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 50 and 89. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
8
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
50
Residue number B
89
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 50 of Tumor necrosis factor receptor superfamily member 18
Cysteine 89 of Tumor necrosis factor receptor superfamily member 18
7khd C 50 C 74
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 50 and 74. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
8
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
50
Residue number B
74
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 50 of Tumor necrosis factor receptor superfamily member 18
Cysteine 74 of Tumor necrosis factor receptor superfamily member 18
7e57 C 29 C 62
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 29 and 62. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
7
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
29
Residue number B
62
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 29 of Tumor necrosis factor receptor superfamily member 18
Cysteine 62 of Tumor necrosis factor receptor superfamily member 18
7e57 C 45 C 69
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 45 and 69. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
7
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
45
Residue number B
69
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 45 of Tumor necrosis factor receptor superfamily member 18
Cysteine 69 of Tumor necrosis factor receptor superfamily member 18
7e57 C 29 C 69
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 29 and 69. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
7
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
29
Residue number B
69
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 29 of Tumor necrosis factor receptor superfamily member 18
Cysteine 69 of Tumor necrosis factor receptor superfamily member 18
7khd D 94 D 128
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 94 and 128. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
94
Residue number B
128
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 94 of Tumor necrosis factor receptor superfamily member 18
Cysteine 128 of Tumor necrosis factor receptor superfamily member 18
7khd C 72 C 85
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 72 and 85. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
8
Half-sphere exposure sum ?
45
Minimum pKa ?
9
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
72
Residue number B
85
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 72 of Tumor necrosis factor receptor superfamily member 18
Cysteine 85 of Tumor necrosis factor receptor superfamily member 18
7khd C 72 C 89
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 72 and 89. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
72
Residue number B
89
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 72 of Tumor necrosis factor receptor superfamily member 18
Cysteine 89 of Tumor necrosis factor receptor superfamily member 18
7khd C 49 C 72
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 49 and 72. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
8
Half-sphere exposure sum ?
46
Minimum pKa ?
9
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
49
Residue number B
72
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 49 of Tumor necrosis factor receptor superfamily member 18
Cysteine 72 of Tumor necrosis factor receptor superfamily member 18
7khd C 94 C 115
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 94 and 115. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
94
Residue number B
115
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 94 of Tumor necrosis factor receptor superfamily member 18
Cysteine 115 of Tumor necrosis factor receptor superfamily member 18
7e57 C 45 C 77
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 45 and 77. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
45
Residue number B
77
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 45 of Tumor necrosis factor receptor superfamily member 18
Cysteine 77 of Tumor necrosis factor receptor superfamily member 18
7khd C 85 C 86
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 85 and 86. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
7khd
Structure name
human gitr-gitrl complex
Structure deposition date
2020-10-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
46
Minimum pKa ?
9
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
85
Residue number B
86
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 85 of Tumor necrosis factor receptor superfamily member 18
Cysteine 86 of Tumor necrosis factor receptor superfamily member 18
7e57 C 44 C 69
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 44 and 69. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7e57
Structure name
crystal structure of murine gitr-gitrl complex
Structure deposition date
2021-02-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
O35714
Residue number A
44
Residue number B
69
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 44 of Tumor necrosis factor receptor superfamily member 18
Cysteine 69 of Tumor necrosis factor receptor superfamily member 18
7law R 112 R 128
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 112 and 128. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7law
Structure name
crystal structure of gitr complex with gitr-l
Structure deposition date
2021-01-07
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
112
Residue number B
128
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 112 of Tumor necrosis factor receptor superfamily member 18
Cysteine 128 of Tumor necrosis factor receptor superfamily member 18
7law S 112 S 115
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 18 between cysteines 112 and 115. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7law
Structure name
crystal structure of gitr complex with gitr-l
Structure deposition date
2021-01-07
Thiol separation (Å)
10
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5U5
Residue number A
112
Residue number B
115
Peptide name
Tumor necrosis factor receptor superfamily member 18
Ligandability
Cysteine 112 of Tumor necrosis factor receptor superfamily member 18
Cysteine 115 of Tumor necrosis factor receptor superfamily member 18
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