a tool for identifying drug-targetable redox-active disulphides

Sorting nexin-10

Intramolecular

Cysteine 35 and cysteine 49

A redox-regulated disulphide may form within Sorting nexin-10 between cysteines 35 and 49.

Details

Redox score ?

78

PDB code

Structure name

crystal structure of human sorting nexin 10 (snx10)

Structure deposition date

2014-03-30

Thiol separation (Å)

2

Half-sphere exposure sum ?

69

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

35

Residue number B

49

Peptide name

Sorting nexin-10

Ligandability

Cysteine 35 of Sorting nexin-10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 49 of Sorting nexin-10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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